Joseph Manigault House is a historic house museum in Charleston, South Carolina that is owned and operated by the Charleston Museum. The house is significant for its Adam style architecture, and was designed by Gabriel Manigault to be the home of his brother, and was completed in 1803. It was declared a National Historic Landmark in 1973.
The SC DAH summary is here. There also is an architectural folly on the property. In 1920, the house was threatened with demolition to make way for a gas station. In response, a group of Charlestonians organized a preservation group which would become the Preservation Society of Charleston.