The James B. Edwards Bridge is a pair of pre-cast concrete box girder bridges that span the Wando River between Mount Pleasant and Daniel Island. It was built in 1989 by the South Carolina Department of Transportation. The bridge is named for James B. Edwards, who was a governor of South Carolina, Secretary of Energy, and long-time president of the Medical University of South Carolina.
The bridge was constructed of pre-cast concrete segments using top-down construction. Segments were transported along already completed spans and put in place from above. This construction method was selected to reduce construction impacts on the marsh areas along the banks of the Wando River.