The Ca' da Mosto is a thirteenth-century palace in Venice, northern Italy, the oldest building on the Grand Canal. It is in the Veneto-Byzantine style, with high narrow arches and distinctive capitals. The features of the palace show its beginnings as a casa-fondaco, the home and workplace of its original merchant owner. A second floor was added at the beginning of the sixteenth century, and a third in the nineteenth.
The Ca' da Mosto currently sits empty, with the high waters of the canal having breached its basement. According to an interview in The Lady, the palace is admired by Francesco da Mosto, a descendant of its eponymous former owners, and is the Venetian building he would most like to see restored.