Masamba is a small river town and kecamatan in the Luwu Regency of South Sulawesi, Indonesia
. The town lies on the Patikala River. It is served by Masamba Airport. Much of the land in the region is swampy coastal plains with mangroves found in its shallow waters. North of the town is Lake Poso. A population of Bugis who are known to be Muslims come from Masamba. A number of these Islamic Bugis moved out of the village into Rompo in the 1940s and into the lowlands of the region into Tabalu and Saatu in the 1950s and 1960s.Rattan trading and making is said to be important to the local economy.Coconuts are also grown near the coast in this region of Sulawesi.