The town's main attraction is Baba's Prasanthi Nilayam ashram, the presence of which has given a huge boost to the local economy, in the form of hotels, lodges, restaurants and shops which are largely frequented by visitors to Prasanthi Nilayam.
Apart from the main Ashram, Puttaparthi has other places of interest like a Hanuman Temple, a Village Mosque and Sathyabhama Temple. Sathyabhama is well known locally as 'Sathyamma' and the temple was built by Late Kondama Raju, grandfather of Sri Sathya Sai Baba. Initially on the outskirts, it is now in the heart of the much grown town of Puttaparthi. Incidentally, another Sathyamma temple was recently constructed by Baba's elder brother Seshama Raju's son on the Bangalore route (10 km from the Ashram) next to the famous Gantla Maremma temple. This (Sathyamma) temple too is believed to be powerful and special poojas and sacrifices are done to the deity on every week. It has started to draw crowds from many nearby villages.
Other major tourist attractions are-the Shiva temple constructed on the site where Baba was born, 'Kalpa Vriksha' or the Wish Fulfilling Tree-a prominent place in the childhood life of Baba and the meditation tree on the hillock on the way to the university.