Zanesville is a city in and the county seat of Muskingum County, Ohio, United States. The population was 25,487 at the 2010 census. Zanesville was named after Ebenezer Zane, who had constructed Zane's Trace, a pioneer road from Wheeling,VA (now WVa) to Maysville KY through present-day Ohio. He gave, in payment, in 1797 to his son-in-law, John McIntire1747-1811, at the point where Zane's Trace met the Muskingum River. With Zanes help, McIntire platted out the town and opened an inn and ferry by 1799. In 1801, Zanesville was officially renamed from Westbourne (Zane's chosen town name). From 1810-1812, the city was the second state capital of Ohio. The National Road runs through Zanesville as U.S. Route 40. Novelist Zane Grey, a descendant of the Zane family, was born in the city. The city has two engineering landmarks: the Muskingum River Canal, designated a National Historic Civil Engineering Landmark; and the Zanesville Y-Bridge, the only such structure in the United States still in use. It is listed on the National Register of Historic Places.