Cisco is a city in Eastland County, Texas, United States. The population was 3,851 at the 2000 census. Conrad Hilton started the Hilton Hotel chain with a single hotel bought in Cisco. Hilton came to Cisco to buy a bank, but the bank cost too much; so he purchased the Mobley Hotel in 1919. The hotel is now a local museum and community Center. During the 1920s, Cisco, like nearby Ranger, Eastland, and Desdemona, was a petroleum boomtown. In 1925, the first annual meeting of the West Texas Historical Association was held in Cisco. The association, formed in 1924, was then based at Hardin-Simmons University in Abilene but moved in 1998 to Texas Tech University in Lubbock.