Pipestone is a city in Pipestone County, Minnesota, United States. It is the county seat of Pipestone County. The city is also the site of Pipestone National Monument. According to the United States Census Bureau, the city has a total area of 3.9 square miles (10 square kilometer), all of it land. U.S. Route 75 and Minnesota State Highways 23 and 30 are three of the main routes in the city.