Oconaluftee is the name of a river valley in the Great Smoky Mountains of North Carolina, located in the Southeastern United States. Formerly the site of a Cherokee village and Appalachian community, the valley's bottomland is now home to the main entrance to the North Carolina section of the Great Smoky Mountains National Park.
The Oconaluftee area parallels the Oconaluftee River as its basin gradually broadens from Smokemont in the north to the Qualla Boundary at its southern tip. The Qualla Boundary, commonly known as Cherokee, North Carolina, comprises the bulk of a federal trust that acts a reservation for the Eastern Band of the Cherokee. The national park lands in Oconaluftee are home to the Oconaluftee Visitor Center, Mingus Mill, and the Mountain Farm Museum. Much of the area is part of the Oconaluftee Archaeological District, which is listed on the National Register of Historic Places.