Maryville is a city in Nodaway County, Missouri, United States.The town, organized on February 14, 1845, was named for Mrs. Mary Graham, wife of Amos Graham, then the county clerk. It is the county seat of Nodaway County. The Maryville micropolitan statistical area consists of Nodaway County. Maryville is home to Northwest Missouri State University, Northwest Technical School, and the Missouri Academy of Science, Mathematics and Computing. Maryville High School is also known for their unique mascot: The Spoofhound.