Ashland is a town in Middlesex County, Massachusetts, United States. It is part of the MetroWest region. The area now known as Ashland was settled in the early 18th century and inhabited prior to that by the Megunko Indians, to which Megunko Hill owes its name. Previously known as "Unionville," Ashland was incorporated in 1846, bearing the name of statesman Henry Clay's Kentucky estate. It is considerably younger than many of the surrounding towns, as Ashland's territory was taken in near-equal parts from the previously established towns of Hopkinton, Holliston, and Framingham. The construction of the Boston & Worcester Railroad, later the Boston & Albany, in the 1830s was key to the early development of the town. Along with the Sudbury River, the Railroad helped to attract numerous mills to develop a bustling boot and shoe industry. However, by constructing three reservoirs along the river in 1878, the Boston Water Board inadvertently stymied further growth until the 20th century, most notably by halting the construction of the Dwight Printing Company's granite mills.