Pocomoke City, dubbed "the friendliest town on the Eastern Shore", is a city in Worcester County, Maryland, United States. Although renamed in a burst of civic enthusiasm in 1878, the city is regularly referred to by its inhabitants simply as Pocomoke. In 1922, the business district of Pocomoke City was destroyed in a large fire, on one side of town this continued up to the church on 3rd street, known as St. Mary's Episcopal Church, claiming the pipe organ, but not the pipes and the downtown was quickly rebuilt. While truck farming declined during the 1900s, the poultry industry rose to take its place. In addition, NASA at Wallops Island, the U.S. Navy, as well as the Coast Guard helped with continued growth by bringing jobs to the area.