Lytle is a city in Atascosa, Bexar, and Medina counties in the U.S. state of Texas. The population was 2,383 at the 2000 census. It is part of the San Antonio Metropolitan Statistical Area. Most of the city lies in Atascosa County; only small portions extend into Bexar and Medina counties. As of the census of 2000, there were 2,383 people, 811 households, and 633 families residing in the city. The population density was 593.4people per square mile (228.9Square kilometers). There were 898 housing units at an average density of 223.6Square meters(86.2Square kilometers). According to the United States Census Bureau, the city has a total area of 4.1square miles (10.5Square kilometers), of which, 4.0square miles (10.4Square kilometers) of it is land and 0.1square miles (0.1Square kilometer) of it (1.23%) is water.