Fort Wayne is the principal city of the Fort Wayne Metropolitan Statistical Area, a metropolitan area that encompasses Allen, Wells, and Whitley counties, for an estimated population of 414,315. In addition to those three counties, the Fort WayneHuntingtonAuburn CSA, a combined statistical area, includes Adams, DeKalb, Huntington, and Noble counties, for a population of 610,015. Fort Wayne is a city in the US state of Indiana and the county seat of Allen County. The population was 253,691 at the 2010 Census making it the 74th largest city in the United States and the second largest in Indiana. The municipality is located in northeastern Indiana, approximately 18 miles (29km) west of the Ohio border and 50 miles (80km) south of the Michigan border.