Indian River is situated at the point where the Sturgeon River flows into Burt Lake and where the Indian River flows out of Burt Lake into Mullett Lake. I-75 passes though the area with two interchanges nearby. Mackinaw City and the Mackinac Bridge are about 25 miles 40 kilometers to the north and Gaylord is 28 miles 45 kilometers to the south. Cheboygan is about 21 miles 34 kilometers to the northeast on M-27. M-68 connects with US 31 at Alanson, 11 miles 18 kilometers to the west and with M-33 about 9 miles 14 kilometers to the east. The Indian River provides a navigable channel between Burt and Mullett lakes.