Floresville is a city in Wilson County, Texas, United States. The population was 5,868 at the 2000 census. It is the county seat of Wilson County. The city is also part of the San Antonio Metropolitan Statistical Area. Floresville was also the birthplace of Vicente T. Ximenes (born 1919), a former member of the Equal Employment Opportunity Commission and a civil rights activist. Floresville was the birthplace of former Texas Governor, United States Secretary of the Treasury, and Republican presidential contender John Bowden Connally, Jr. , and his seven siblings, including actor Merrill Connally and Wayne Connally , a former member of both houses of the Texas State Legislature. The Connally Memorial Medical Center in Floresville is named for John, Merrill, and Wayne Connally.