Fifty-Six is a city in Stone County, Arkansas, United States. As of the 2000 census, the city had a total population of 163. As of the census of 2000, there were 163 people, 71 households, and 51 families residing in the city. The population density was 79.1 people per square mile (30.6/km²). There were 87 housing units at an average density of 42.2 per square mile (16.3/km²). The racial makeup of the city was 97.55% White and 2.45% Native American. 1.84% of the population were Hispanic or Latino of any race.
There were 71 households out of which 25.4% had children under the age of 18 living with them, 64.8% were married couples living together, 7.0% had a female householder with no husband present, and 26.8% were non-families. 26.8% of all households were made up of individuals and 12.7% had someone living alone who was 65 years of age or older. The average household size was 2.30 and the average family size was 2.69.