Doniphan is a city in Ripley County, Missouri, United States. Doniphan, Missouri is best known for its placement at the heart of the Current River, one of the cleanest rivers in the United States. It draws tourism and is a main attraction of the town. There were 951 housing units at an average density of 695.3 per square mile (268.0/square kilometers). The racial makeup of the city was 98.60% White, 0.36% Native American, 0.47% Asian, 0.05% Pacific Islander, 0.10% from other races, and 0.41% from two or more races.