Tubutama is a town, and the surrounding municipality of the same name, in the north-west of the Mexican state of Sonora. It was founded in the late 17th century by Fr. Francisco Eusebio Kino. It was the headquarters of religious administration for the entire Pimeria Alta during much of the Jesuit and Franciscan period of Spanish colonial rule. The municipal area is 1,351.60 km2 (521.86 sq mi) and the population was 1,798 in 2005. The main economic activities are cattle raising (11,000 head in 2005) and subsistence farming.
Tourists can visit the Mission of San Pedro and San Pablo, built by Jesuit missionary Eusebio Francisco Kino at the end of the eighteenth century. The arched entrance is Mudéjar and in the interior the transept is dedicated to the Passion of Christ and the altarpiece has sculptured instruments of the Passion: crown of thorns, scourge, nails, tongs, ladder, and lances. A sculptured serpent crawls beneath an upper niche in the same altarpiece. This recess now holds a carved statue of Our Lady of Aránzazu, an image of the Virgin Mary as she appeared at Aránzazu in the autonomous community of the Basque Country, in northern Spain.