Santi Aquila e Priscilla is a Roman Catholic church dedicated to saints Aquila and Priscilla in the quartiere Portuense (Q.XI) of Rome, on via Pietro Blaserna. The church was consecrated on November 15, 1992. In 1994, John Paul II designated it as a cardinal's titular church, and the current Cardinal-Priest is Cardinal Jaime Lucas Ortega y Alamino, Archbishop of Havana.
The church is elliptical. The chancel is dominated by a large painting of the Madonna and a massive pipe organ. At the side is the chapel of the Blessed Sacrament illuminated by stained glass. A nursery is located at the bottom of the church, near the main entrance.