The church of Saint Agnes Outside the Wall (Italian: Sant'Agnese fuori la mura) is a titulus church, minor basilica in Rome, on a site sloping down from the Via Nomentana, which runs north-east out of the city, still under its ancient name. What are said to be the remains of Saint Agnes are below the high altar. The church is over one of the catacombs of Rome, where Agnes was originally buried, and which may still be visited from the church.
The church was built by Pope Honorius I in the 7th century, and largely retains its original structure, despite many changes to the decoration. In particular the mosaic in the apse of Agnes, Honorius and another Pope is largely in its original condition. The current Cardinal Priest of the Titulus S. Agnetis Extra moenia is Camillo Ruini.