Lai Chi Kok Road is a road in the western part of New Kowloon, Hong Kong. It links Lai Chi Kok to Mong Kok, via Tai Kok Tsui, Sham Shui Po and Cheung Sha Wan. It starts from the junction with Nathan Road near Pioneer Centre in the south and ends near Mei Foo Sun Chuen. The road is bidirection except the section Lai Chi Kok, between the junction with Butterfly Valley Road and Mei Foo Sun Chuen, where it serves New Territories-bound traffic. The Kowloon-bound is left to Cheung Sha Wan Road, separated by the flyover of Kwai Chung Road.
The section in Sham Shui Po is historically the camp of British Army, where once a detention camp for prisoners of war during Japanese Occupation of Hong Kong. The Sham Shui Po Police Station at the junction of Yen Chow Street is also historical.
The historical 4-storey building Lui Seng Chun (雷生春) is on 119 Lai Chi Kok Road. It has been restored by the Government of Hong Kong and will likely feature a traditional Chinese tea house when it re-opens. The road once hosted shipyards, fish, meat and vegetable wholesale markets, which were moved closer to the coast after extensive reclamation.