Ukkusissat is a settlement in the Qaasuitsup municipality, in northwestern Greenland. The population of the settlement was 170 in 2010. Fishing is the main occupation in Ukkusissat, with the fish processing plant located at the harbour; many inhabitants employed at Royal Greenland.
Reinvigoration of mining activities in the nearby Maamorilik site−located northeast of the settlement on the northern side of Perlerfiup Kangerlua−will provide an economic boost to the local economy. The community in Ukkusissat is served by Pilersuisoq, an all-purpose communal store.
Tourism is underdeveloped, although during summer the settlement is visited by cruise ships, such as Norway's Hurtigruten. The harbour in Ukkusissat cannot handle ships large ships due to shallow coastal waters. Air Greenland serves the village as part of government contract, with flights between Ukkusissat Heliport and Uummannaq Heliport. Check-in for the helicopter flights is administered at Pilersuisoq.