Aappilattoq is a village in the Kujalleq municipality in southern Greenland. The name means "sea anemone" in the Greenlandic language. The area of Aappilattoq has been inhabited since the 19th century, but the present-day village was founded in 1922.
The settlement has a heliport operated by Air Greenland. The village is served as part of government contract, with mostly cargo helicopter flights. The main transportation routes are via sea. The village is practically inaccessible via land due to its remote location and the surrounding mountain region.