La Motte-Picquet - Grenelle is a station of the Paris Métro, at the interconnection of lines 6, 8 and 10 in the 15th arrondissement, near the 7th arrondissement. The station combines underground and elevated platforms. It is named after the Avenue de la Motte-Picquet and the Boulevard de Grenelle. It is a major Paris Metro interconnection on the Rive Gauche, and the most important west of Montparnasse.
The elevated station first opened on 24 April 1906, as part of the extension of line 2 Sud (2 South) from Passy to Place d'Italie. On 14 October 1907, line 2 Sud was incorporated into line 5. On 12 October 1942 the section of line 5 between Étoile and Place d'Italie, including La Motte-Picquet Grenelle, was transferred to Line 6.