Chorlton Brook is a stream in Greater Manchester, England. It heads westward through Chorlton-cum-Hardy, having been formed at the confluence of Platt Brook and Shaw Brook (or Red Lion Brook), and after passing north of Chorltonville it flows through Chorlton Ees into The River Mersey upstream of Sale Water Park.
Chorlton Ees is an area of floodplain on the right bank of the Mersey once used as water meadow and pasture. Gradually flood control measures were developed to reduce the disruption caused by periodic floods. In the 19th century it became an area of waste disposal and the Withington Sewage Farm was established on part of the site of which remains may still be seen. (At that time the area was in Withington Urban District.) The tendency for housing to be needed for an expanding population led to Chorltonville and other much smaller plots encroaching on the meadowland. More recently it has been converted in parts to a nature reserve: Chorlton Ees and Ivy Green Nature Reserve.