Lupin Mine was a gold mine in Nunavut Territory, Canada. It opened in 1982 and was originally owned and operated by Echo Bay Mines Limited, who in 2003 became a fully owned subsidiary of Kinross Gold Corporation. The mine ceased production briefly in August 2003, but was restarted in early 2004 to recover old stope pillars with a reduced crew. The mine closed again in February 2005 and, in 2006, the assets were sold to Wolfden Resources Limited and subsequently to Zinifex.
Plans are ongoing to use the production plant to operate a proposed mine at Izok Lake, located to the south west near the Nunavut and Northwest Territories border. Lupin may also be reopened to recover the last available ore reserves. During the winter, the mine is served by the Tibbitt to Contwoyto Winter Road.