The Cunene River or Kunene River (Namibian spelling) is a river in South western Africa. It flows from the Angola highlands south to the border with Namibia. It then flows west along the border until it reaches the Atlantic Ocean. It is one of the few perennial rivers in the region. It is about 1,050 kilometres (652 mi) long, with a drainage basin 106,560 square kilometres (41,143 sq mi) in area. Its mean annual discharge is 174 m³/s (6,145 cfs) at its mouth.
The Epupa Falls lie on the river. Olushandja Dam dams the river. The Namibian government has proposed building the Epupa Dam, a controversial hydroelectric dam on the Cunene. The dam may threaten the local ecosystem and therefore the economic basis of the local Himba ethnic group.