Nancy Creek is a 16.3-mile-long (26.2 km) stream in northern Atlanta, Georgia, United States. It begins in far northern DeKalb County, just north of Chamblee, and flows southwestward into Fulton County, through the far southeast corner of Sandy Springs, then through the Buckhead area of Atlanta.
It empties into Peachtree Creek, which then flows into the Chattahoochee River, south of Vinings and Paces. The Chattahoochee eventually joins with the Flint River to create the Apalachicola River, which flows into the Gulf of Mexico. The North Fork Nancy Creek is a major tributary, while Little Nancy Creek tends to run low or dry.