Kisizi or Kisiizi is a community centred around Kisiizi Hospital in the Rukungiri District of south-west Uganda. The town of Kisiizi is located in Rukungiri District, in southwestern Uganda, approximately 22 kilometres (14 mi), by road, south of the district headquarters at Rukungiri. This location is approximately 46 kilometres (29 mi), by road, north of Kabale, the largest city in the sub-region.
Kisiizi owes its existence to the presence of Kisiizi Hospital. Kisiizi Hospital also has a primary school, which has close links with a secondary school named Rubirizi Secondary School. The town is split into upper and lower Kisiizi, separated by a distance of about a five (5) minutes journey by car. Both the primary school and hospital are located in lower Kisiizi, along with a small market, an internet cafe, and various residential buildings. The Internet Cafe (run by MicroCare Limited, in co-operation with Project Trust volunteers) also offers daily IT tuition to local school and hospital staff. Upper Kisiizi consists mainly of shops and housing with a number of small bars.