The Metropolitan Cathedral Church of the Holy Cross, Our Lady of Regla, and St Francis of Assisi is the main ecclesiastical building of the Catholic Church in Chihuahua, Chihuahua, Mexico. It is considered perhaps the finest example of colonial architecture in northern Mexico and dates from 1725. The cathedral is also the seat of the Roman Catholic Archdiocese of Chihuahua. The current archbishop is His Grace, the Most Reverend Constancio Miranda Weckmann.
The building is situated on the Plaza de Armas. It is designed in the Spanish Baroque style, and is in the form of a latin cross, with a dome above the crossing.