The centre is built on the site of the Hongkong and Kowloon Wharf and Godown, one of colonial Hong Kong's original commercial wharfage and dockside warehousing complexes. Harbour City is still owned by The Wharf Limited, which was formed in 1886 to operate the godown but has since grown to be a major commercial force in Hong Kong.
The mall features many branded boutiques, such as MCM, Louis Vuitton, Salvatore Ferragamo, Shiatzy Chen, Prada, Yves Saint Laurent, Polo Ralph Lauren, Versace, Burberry, and Hugo Boss. The mall also has two cinemas at both ends, the Grand Ocean and the Grand Gateway; both are operated by Golden Harvest. It is home to the largest Toys "R" Us location in Hong Kong, and there is a large Lane Crawford in the Hongkong Hotel portion of the mall.