The Museo Chileno de Arte Precolombino (Chilean Museum of Pre-Columbian Art) is an art museum dedicated to the study and display of pre-Columbian artworks and artefacts from Central and South America. The museum is located in the city centre of Santiago, the capital of Chile.
The museum was founded by the prominent Chilean architect and antiquities collector Sergio Larrain Garcia-Moreno, who had sought premises for the display and preservation of his private collection of pre-Columbian artefacts acquired over the course of nearly fifty years. With the support of Santiago's municipal government at the time, Garcia-Moreno secured the building and established the museum's curatorial institution. The museum first opened in December 1981.