The II Antofagasta Region is one of Chile's fifteen first-order administrative divisions. It comprises three provinces, Antofagasta, El Loa and Tocopilla. It is bordered to the north by Tarapacá and by Atacama to the south and is the second-largest region of Chile.
The capital of the region is the port city of Antofagasta, another important city is Calama.Antofagasta's history is divided, as the territory, in two sections, the coastal region and the highlands plateau or altiplano around the Andes. In pre-Columbian times, the coastline was populated by nomadic fishing clans of Changos Indians, of which very little is known, due to very limited contact with the Spanish conquerors.